067 Eruptive lichen planus associated with the chronic lymphocytic leukemia: a case report
نویسندگان
چکیده
Chronic lymphocytic leukemia (CLL) is a malignant lymphoproliferative disease characterized by the accumulation of immature monoclonal lymphocytes in blood cells, bone marrow, spleen and lymph nodes. Patients with manifest different types skin lesions that occur about 25% cases. These can be divided into a) specific lesions, b) cutaneous manifestations closely related to but without leukemoid infiltrate c) associations various dermatologic conditions. Lichen planus (LP) an inflammatory condition characteristic clinical histopathological findings. The eruptive variant LP, also called exanthematous or generalized has rarely been reported literature adults. We report case lichen - like eruption as associated CLL. A 52-year-old caucasian female patient presented dermatology clinic for rapidly spreading, disseminated, erythematous, flat-topped, polygonal papules macules; pruritic appear over trunk all four extremities. started manifesting approximately one month prior evaluation. Her past medical history notable B-cell chronic since 2019 haematological treatment. For definite diagnosis, biopsy was performed examination revealed changes led diagnosis planus. differential implied distinction between considerable number diseases, especially (leukemids). received topical systemic treatments slight improvement. Therefore, clinicians need aware diversity CLL-associated, including lesions.
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ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 2022
ISSN: ['1523-1747', '0022-202X']
DOI: https://doi.org/10.1016/j.jid.2022.09.076